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KMID : 0383820150780030227
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Tuberculosis and Respiratory Diseases
2015 Volume.78 No. 3 p.227 ~ p.231
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Changes in Diagnostic Methods for Pulmonary Tuberculosis between 2005 and 2013
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Ahn Bin
Kim Joo-Hae
Yoo Chul-Gyu
Kim Young-Whan
Han Sung-Koo
Yim Jae-Joon
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Abstract
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Background : Diagnostic methods for pulmonary tuberculosis (TB) have recently advanced. The aim of this study was to evaluate the changes in TB diagnostic tests that prompted the initiation of anti-TB treatment over time in South Korea, an industrialized country with an intermediate TB burden.
Materials and Methods : Patients diagnosed with pulmonary TB in the first halves of 2005 and 2013 at a tertiary referral hospital were included. Diagnostic methods that prompted the initiation of anti-TB treatment were compared between the 2 groups of patients.
Results : A greater proportion of patients were diagnosed with pulmonary TB using bronchoscopy in 2013 than in 2005 (26.7% vs. 6.6%, respectively; p<0.001), while the proportion of patients clinically diagnosed with pulmonary TB was lower in 2013 than in 2005 (24.7% vs. 49.0%, respectively; p<0.001). Additionally, more patients started anti-TB treatment based on positive polymerase chain reaction (PCR) results for Mycobacterium tuberculosis DNA in 2013 than in 2005 (47.3% vs. 7.9%, respectively; p<0.001).
Conclusion : The initiation of treatment for pulmonary TB in South Korea has become more frequently based on PCR and the use of bronchoscopic specimens.
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KEYWORD
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Tuberculosis, Pulmonary, Diagnosis, Bronchoscopy, Nucleic Acid Amplification Techniques
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